Currently married to a retired baseball player, Brooke Tammaro Villone, started her modeling career at the age of 15. The romance between Ron and Brooke started in 2002 when they met in a promotional event. Ron admitted that he has already known her because one of her modeling shots hung in his locker. Ron Villone is a left-handed relief pitcher.

In 2010, Brooke gave birth to their daughter whom they named Sofia. Ron has two other children in past relationships. Currently, the family, together with Megan (b. 1996) and Ronald III (b. 1997) resides in Upper Saddle River in New Jersey.